Fadi Kayali, Muhamad A Janjua, Damian A Laber, Donald Miller, 1100 Goetz H KloeckerUniversity of Louisville, James Graham Brown Cancer Center, Louisville, KY, USABackground: In vitro digoxin sensitizes cancer cells to the induction of apoptosis by chemotherapy.Inhibition of the Na/K-ATPase enzyme by ouabain disturbs the intracellular ion compositio
Customers often get attracted by lucrative deals and Tie Gift Box discounts offered by firms.These, attracted customers are termed as encouraged arrivals.In this paper, we developed a multi-server Feedback Markovian queuing model with encouraged arrivals, customer impatience, and retention of impatient customers.The stationary system size probabili
Bronchiolitis obliterans syndrome (BOS) may develop after either lung or haematopoietic stem cell transplantation (HSCT), with similarities in histopathological features and clinical manifestations.However, there are differences in the contributory factors and clinical trajectories between the two conditions.BOS after HSCT occurs due to systemic gr
Clear cell renal cell carcinoma (ccRCC) is the most common and most aggressive form of renal cell cancer (RCC).The incidence of RCC has increased steadily in recent years.The pathogenesis of renal cell cancer remains poorly understood.Many of the tumor suppressor genes, oncogenes, and dysregulated pathways in ccRCC need to be Undercounter Freezers
USP25m is the muscle isoform of the CHOLESTEROL CONTROL deubiquitinating (DUB) enzyme USP25.Similarly to most DUBs, data on USP25 regulation and substrate recognition is scarce.In silico analysis predicted three ubiquitin binding domains (UBDs) at the N-terminus: one ubiquitin-associated domain (UBA) and two ubiquitin-interacting motifs (UIMs), whe